The bed bug may be just as dangerous as its sinister cousin,    the triatomine, or kissing bug. A new study from Penn    Medicine researchers in the Center for Clinical Epidemiology    and Biostatistics demonstrated that bed bugs, like the    triatomines, can transmit Trypanosoma cruzi, the parasite that    causes Chagas disease, one of the most prevalent and deadly    diseases in the Americas.  
    The role of the bloodsucking triatomine bugs as vectors of    Chagas diseasewhich affects 6 to 8 million worldwide, mostly    in Latin America, and kills about 50,000 a yearhas long been    recognized. The insects infect people not through their bite    but feces, which they deposit on their sleeping host, often    around the face, after feeding. Bed bugs, on the other hand,    are usually considered disease-free nuisances whose victims are    left with only itchy welts from bites and sleepless nights.  
    In a study published online in the American Journal of    Tropical Medicine and Hygiene, senior author Michael Z.    Levy, PhD, assistant professor in the department of    Biostatistics and Epidemiology at the University of    Pennsylvanias Perelman School of Medicine, and researchers at    the Universidad Peruana Cayetano Heredia in Peru conducted a    series of laboratory experiments that demonstrated    bi-directional transmission of T. cruzi between mice and bed    bugs.  
    In the first experiment run at the Zoonotic Disease Research    Center in Arequipa, Peru, the researchers exposed 10 mice    infected with the parasite to 20 uninfected bed bugs every    three days for a month. Of about 2,000 bed bugs used in the    experiment, the majority acquired T. cruzi after feeding on the    mice. In a separate experiment to test transmission from    bug to mouse, they found that 9 out of 12 (75 percent)    uninfected mice acquired the parasite after each one lived for    30 days with 20 infected bed bugs.  
    In a third experiment, investigators succeeded in infecting    mice by placing feces of infected bed bugs on the animals skin    that had either been inflamed by bed bug bites, or scraped with    a needle. Four out of 10 mice (40 percent) acquired the    parasite by this manner; 1 out of 5 (20 percent) were infected    when the skin was broken by the insects bites only. A final    experiment performed at the Penn bed bug lab in Philadelphia    demonstrated that bed bugs, like triatomines, defecate when    they feed.  
    Weve shown that the bed bug can acquire and transmit the    parasite. Our next step is to determine whether they are, or    will become, an important player in the epidemiology of Chagas    disease, Levy said. There are some reasons to worrybed bugs    have more frequent contact with people than kissing bugs, and    there are more of them in infested houses, giving them ample    opportunity to transmit the parasite. But perhaps there is    something important we dont yet understand about them that    mitigates the threat.  
    T. cruzi is also especially at home in the guts of bed    bugs. Ive never seen so many parasites in an insect,    said Renzo Salazar, a biologist at the Universidad Peruana    Cayetano Heredia and co-author on the study. I expected a    scenario with very low infection, but we found many    parasitesthey really replicate well in the gut of the bed    bugs.  
    Wicked Cousins  
    Bed bugs and kissing bugs are distant cousins but share many    striking similarities. Both insects hide in household cracks    and crevices waiting for nightfall and the opportunity to feed    on sleeping hosts. They are from the same order of insects    (Hemiptera) and both only feed on blood. (One main    difference is their size: kissing bugs are five times as big as    a bed bug). With so much in common, it seemed logical to the    authors that the kissing bugs most infamous trait, the    transmission of T. cruzi, is also shared by the bed bug.  
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Study Shows Bed Bugs Transmit Parasite That Causes Deadly ...